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Updated: Jul 13, 2026

Investigations on the Ga(III) Complex of EOB-DTPA and Its 68Ga Radiolabeled Analogue
Published on: August 17, 2016
55Cobalt complexes with pendant carbohydrates as potential PET imaging agents
Cara L Ferreira1, Suzanne Lapi, Jennifer Steele
1TRIUMF, 4004 Wesbrook Mall, Vancouver, BC, Canada V6T 2A3.
Abstract:
Bis-ligand cobalt(II) complexes of four 3-hydroxy-4-pyridinone ligands with pendant carbohydrates were synthesized and examined for their potential as radiopharmaceuticals. Non-radioactive complexes were prepared on the macroscopic scale and characterized by elemental analysis, mass spectrometry, IR and UV/visible spectroscopy. Facile radiolabeling produced the 55Co complexes in high radiochemical yields (>95%). Identification of the radiolabeled compounds was accomplished by HPLC comparison with the corresponding non-radioactive complexes.
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