Related Experiment Video

Updated: Jul 13, 2026

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
05:21

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

Published on: August 14, 2019

Influenza vaccination in secondary prevention: an opportunity missed

Vera Bittner1, Bonnie K Sanderson

  • 1Division of Cardiovascular Disease, Preventive Cardiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. vbittner@uab.edu

Journal of Cardiopulmonary Rehabilitation and Prevention
|August 2, 2007
PubMed

Insights

Influenza vaccination rates are suboptimal in cardiac rehabilitation patients. Younger, nonwhite individuals without diabetes or COPD are less likely to be vaccinated, necessitating targeted interventions.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Public Health

Background:

  • Influenza vaccination (FluVacc) is a Class I recommendation for secondary prevention in patients with coronary heart disease (CHD).
  • Limited data exists on FluVacc prevalence and its correlates in CHD patients undergoing cardiac rehabilitation.

Purpose of the Study:

  • To determine the prevalence and identify independent correlates of influenza vaccination among patients with coronary heart disease in a cardiac rehabilitation program.

Main Methods:

  • Analysis of data from 1,051 CHD patients in an academic medical center's cardiac rehabilitation program (1996-2006).
  • Comparison of FluVacc proportions across demographic, clinical, and comorbidity subgroups.
  • Multivariate logistic regression to identify independent predictors of FluVacc receipt.

Main Results:

  • Overall, 52% of patients reported up-to-date FluVacc.
  • Independent correlates of FluVacc included older age (OR 2.7), white race (OR 1.5), diabetes (OR 2.2), and chronic obstructive pulmonary disease (OR 1.8).
  • Lower vaccination rates were observed in younger, nonwhite patients without diabetes or COPD.

Conclusions:

  • Influenza vaccination rates are suboptimal in CHD patients within cardiac rehabilitation settings.
  • Targeted interventions are crucial to improve vaccination uptake in underrepresented patient groups.
  • Enhancing FluVacc rates can contribute to better secondary prevention outcomes for CHD patients.
Abstract

More Related Videos

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes08:52

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes

Published on: July 26, 2019

A Precise Pathogen Delivery and Recovery System for Murine Models of Secondary Bacterial Pneumonia13:45

A Precise Pathogen Delivery and Recovery System for Murine Models of Secondary Bacterial Pneumonia

Published on: September 21, 2019

Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Influenza01:27

Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...