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Poliomyelitis in France: epidemiology and vaccination status
1Department of Public Health, Centre Hospitalier Universitaire, Tours, France.
Insights
France has virtually eliminated paralytic poliomyelitis through widespread infant immunization with enhanced-potency inactivated poliovirus vaccine (eIPV) and DTP. Continued vaccination and surveillance are crucial for eradicating wild poliovirus.
Area of Science:
- Public Health
- Vaccinology
- Epidemiology
Background:
- Paralytic poliomyelitis remains a global health concern.
- France utilizes enhanced-potency inactivated poliovirus vaccine (eIPV) combined with diphtheria-tetanus-pertussis (DTP) for infant immunization.
- High vaccination coverage is essential for disease control.
Purpose of the Study:
- To assess the impact of the eIPV vaccination program in France.
- To evaluate the current status of poliomyelitis eradication in the country.
- To provide recommendations for future polio eradication efforts.
Main Methods:
- Analysis of national immunization coverage data.
- Review of reported cases of paralytic poliomyelitis.
- Surveillance data for wild poliovirus circulation.
Main Results:
- Ninety-five percent of infants receive four doses of DTP-eIPV by 24 months.
- No vaccine-associated paralysis cases reported since 1983.
- Only three wild indigenous polio cases reported in 1988-1989; none in 1990.
Conclusions:
- The eIPV vaccination program has been highly effective in controlling poliomyelitis in France.
- Paralytic poliomyelitis is virtually eliminated in France.
- Reinforced vaccination programs and surveillance are necessary to achieve global wild poliovirus eradication.
Abstract:
In France, infants are immunized against paralytic poliomyelitis with enhanced-potency inactivated poliovirus vaccine (eIPV) combined with the diphtheria-tetanus-pertussis vaccine (DTP). Ninety-five percent of all infants in France have received four doses of DTP-eIPV by 24 months of age. No cases of vaccine-associated paralysis, among either recipients or those in contact with recipients, have been reported since 1983, when eIPV became the vaccine of choice. Only three wild indigenous cases have been reported among unvaccinated children in 1988 and 1989, with no cases reported in 1990. Although paralytic poliomyelitis has been virtually eliminated in France, vaccination programs as well as active surveillance of the community and environment for poliovirus circulation should be reinforced to reach the goal of wild poliovirus eradication.