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Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET
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Urological malignancy after renal transplantation.

Dler Besarani1, David Cranston

  • 1Department of Urology, Churchill Hospital, Oxford Radcliffe Hospitals NHS Trust, Oxford, UK. dLer@doctors.org.uk

BJU International
|August 3, 2007
PubMed
Summary

Kidney transplant recipients have a higher risk of developing new urological cancers. Early detection through surveillance and adjusting immunosuppression may improve outcomes for these patients.

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Area of Science:

  • Urology
  • Oncology
  • Transplantation Medicine

Background:

  • Immunosuppression post-solid-organ transplant increases de novo malignancy risk.
  • Urological cancers are a significant concern in kidney transplant recipients.

Purpose of the Study:

  • To analyze the incidence of de novo urological malignancies in UK kidney transplant recipients.
  • To identify trends and potential risk factors for urological cancer post-renal transplantation.

Main Methods:

  • Utilized the UK Transplant Registry (UKTR) database from September 1999 to January 2006.
  • Included 10,847 kidney transplant recipients, excluding skin cancers.
  • Identified 214 cases (1.9%) of subsequent urological malignancy.

Main Results:

  • A 1.9% incidence of de novo urological malignancy was observed in 10,847 kidney transplant recipients.
  • The UKTR database provided insights into post-transplant urological cancer development.
  • Data on pre-transplant cancer status was not available.

Conclusions:

  • Regular surveillance for early diagnosis of urological malignancies is recommended.
  • Adjusting immunosuppression regimens may be beneficial in managing post-transplant cancer risk.
  • Metastatic disease requires chemotherapy alongside immunosuppression modification.