Related Experiment Video
Updated: Jul 13, 2026

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Continuous subglottic suction is effective for prevention of ventilator associated pneumonia
Rahul Gujadhur1, Bruce W Helme, Aliu Sanni
1Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle upon-Tyne NE7 7DN, UK.
Insights
Subglottic suction effectively prevents ventilator-associated pneumonia (VAP) in high-risk cardiac surgery patients. While benefits are lower in elective cases, it remains a cost-effective VAP prevention strategy.
Area of Science:
- Cardiac Surgery
- Intensive Care Medicine
- Infectious Disease Prevention
Background:
- Ventilator-associated pneumonia (VAP) is a significant complication following cardiac surgery.
- Current preventative measures for VAP require ongoing evaluation for efficacy and cost-effectiveness.
Purpose of the Study:
- To evaluate the effectiveness of subglottic suction in preventing VAP in cardiac surgery patients.
- To synthesize the best available evidence on subglottic suction for VAP prevention.
Main Methods:
- A systematic search identified 457 relevant papers.
- 13 high-quality studies were selected to provide the best evidence.
- Data on patient groups, study types, outcomes, and results were tabulated.
Main Results:
- Subglottic suction significantly reduces VAP incidence in high-risk patients (NNT=8 for ventilation >3 days).
- The benefit of subglottic suction is less pronounced in elective cardiac surgery patients.
- The intervention is not widely used but shows potential for high cost-effectiveness.
Conclusions:
- Subglottic suction is an effective VAP preventative measure, particularly for high-risk cardiac surgery patients.
- Despite marginal benefits in some groups, its implementation may be highly cost-effective.
- Further adoption of subglottic suction is recommended for VAP reduction.
Abstract:
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether subglottic suction is an effective preventative measure for ventilator associated pneumonia (VAP) after cardiac surgery. Altogether 457 papers were found using the reported search, of which 13 presented the best evidence to answer the clinical question. The author, journal, date and country of publication, patient group studied, study type, relevant outcomes, results, and study weaknesses of these papers are tabulated. We conclude Subglottic suction significantly reduces the incidence of VAP in high risk patients (NNT of 8 if ventilated over 3 days), although the benefit is lower in elective cardiac patients. Subglottic suction is currently not commonly used, but even with marginal benefits, its use is likely to be highly cost effective.
Related Concept Videos
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Suctioning the Nasopharyngeal Airway
Equipment Required
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Tracheostomy Suctioning II: Procedure
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
