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Internal mammary revascularization in patients with variant angina and normal coronary arteries
Takayuki Ono1, Takeki Ohashi, Teiji Asakura
1Department of Cardiothoracic Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan. takohno@hotmail.com
Insights
Coronary artery bypass surgery using internal mammary artery grafts effectively treated patients with severe variant angina and normal coronary arteries. This approach offers a new option for managing intractable coronary artery spasm.
Area of Science:
- Cardiology
- Vascular Surgery
Background:
- Variant angina (Prinzmetal's angina) refractory to medical therapy presents significant management challenges.
- Coronary revascularization is typically contraindicated in isolated coronary spasm without obstructive disease.
Purpose of the Study:
- To evaluate the efficacy of coronary artery bypass surgery with internal mammary artery (IMA) grafts in patients with medically intractable Prinzmetal's angina and normal coronary arteries.
Main Methods:
- Two patients with life-threatening, intractable Prinzmetal's angina and normal coronary arteries underwent coronary artery bypass surgery using IMA grafts.
- Postoperative angiography was performed to assess graft function during spastic attacks.
Main Results:
- Both patients experienced rapid and complete remission of coronary spastic attacks following surgery.
- Postoperative angiography demonstrated the functional mechanism of the IMA graft during coronary artery spasm.
Conclusions:
- Coronary artery bypass surgery with IMA grafts can be a successful treatment for patients with isolated coronary spasm and normal coronary arteries.
- This surgical approach provides a viable alternative for managing severe, refractory variant angina.
Abstract:
Patients with variant angina refractory to medical therapy pose a difficult management problem. In patients with discrete obstructive lesions, coronary revascularization may be helpful. However, it has been widely accepted that coronary revascularization is contraindicated in patients with isolated coronary spasm without evidence of obstructive disease. Here we describe the two patients with life-threatening, medically intractable Prinzmetal's angina and angiographically normal coronary arteries, both of whom underwent coronary-artery-bypass surgery with the internal-mammary-artery (IMA) graft. These operations resulted in rapid, complete remission of coronary spastic attacks in both patients. Postoperative angiography reveals how the IMA graft works during spastic attacks.
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