Internal mammary revascularization in patients with variant angina and normal coronary arteries

Takayuki Ono1, Takeki Ohashi, Teiji Asakura

  • 1Department of Cardiothoracic Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan. takohno@hotmail.com

Insights

Coronary artery bypass surgery using internal mammary artery grafts effectively treated patients with severe variant angina and normal coronary arteries. This approach offers a new option for managing intractable coronary artery spasm.

Area of Science:

  • Cardiology
  • Vascular Surgery

Background:

  • Variant angina (Prinzmetal's angina) refractory to medical therapy presents significant management challenges.
  • Coronary revascularization is typically contraindicated in isolated coronary spasm without obstructive disease.

Purpose of the Study:

  • To evaluate the efficacy of coronary artery bypass surgery with internal mammary artery (IMA) grafts in patients with medically intractable Prinzmetal's angina and normal coronary arteries.

Main Methods:

  • Two patients with life-threatening, intractable Prinzmetal's angina and normal coronary arteries underwent coronary artery bypass surgery using IMA grafts.
  • Postoperative angiography was performed to assess graft function during spastic attacks.

Main Results:

  • Both patients experienced rapid and complete remission of coronary spastic attacks following surgery.
  • Postoperative angiography demonstrated the functional mechanism of the IMA graft during coronary artery spasm.

Conclusions:

  • Coronary artery bypass surgery with IMA grafts can be a successful treatment for patients with isolated coronary spasm and normal coronary arteries.
  • This surgical approach provides a viable alternative for managing severe, refractory variant angina.