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Cardiac surgery in patients with systemic lupus erythematosus

Cheng-Hsin Lin1, Meng-Lin Lee, Ron-Bin Hsu

  • 1Department of Surgery, National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7, Chung-Shan S. Rd. Taipei, Taiwan 100, ROC.

Interactive Cardiovascular and Thoracic Surgery
|August 3, 2007
PubMed

Insights

Cardiac surgery in patients with systemic lupus erythematosus (SLE) is uncommon. Despite frequent postoperative complications, this study indicates that cardiac operations are feasible in SLE patients.

Area of Science:

  • Cardiology
  • Rheumatology
  • Surgical Outcomes

Background:

  • Cardiac surgery is rarely performed in patients with systemic lupus erythematosus (SLE).
  • Clinical outcomes data for cardiac operations in SLE patients are limited to small case series.

Purpose of the Study:

  • To evaluate the clinical outcomes of cardiac surgery in patients diagnosed with systemic lupus erythematosus (SLE).

Main Methods:

  • A retrospective review of 9 patients with SLE who underwent cardiac surgery between January 1996 and March 2005.
  • Surgical procedures included coronary artery bypass grafting (CABG), valve replacement, and heart-kidney transplantation.
  • Follow-up data were collected to assess short-term and long-term outcomes.

Main Results:

  • The in-hospital mortality rate was 11% (1/9).
  • Major postoperative complications, such as bleeding and arrhythmias, occurred in 44% of patients.
  • Late deaths occurred due to sudden cardiac death and sepsis, with a median follow-up of 23 months.

Conclusions:

  • Cardiac operations can be performed in patients with systemic lupus erythematosus (SLE).
  • Postoperative complications are common, necessitating careful patient selection and management.

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