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[Determination of morusin in cortex mori]
Yu-ying Zong1, Siu-po Ip, Ting-xia Dong
1School of Chinese Medicine, The Chinese University of Hongkong, Shatin, Hongkong, China.
Summary
Morusin content in Sangbaipi (Cortex Mori) varies by commercial grade, species, and region. Factors like outer layer color and thickness influence morusin levels, aiding quality assessment.
Area of Science:
- Pharmacognosy
- Analytical Chemistry
- Traditional Chinese Medicine
Context:
- Sangbaipi (Cortex Mori) is a crucial component in Traditional Chinese Medicine.
- Variability in medicinal plant quality impacts therapeutic efficacy.
- Standardized quality assessment methods are essential for herbal medicines.
Purpose:
- To quantify morusin content in various commercial grades and species of Cortex Mori.
- To investigate the influence of geographical origin on morusin levels.
- To establish correlations between physical characteristics of Cortex Mori and its morusin content.
Summary:
- High-performance liquid chromatography (HPLC) was employed to determine morusin concentrations.
- Morusin content significantly differed based on the presence of a yellow-brown outer layer and the thickness of the Cortex Mori samples.
- The developed HPLC method demonstrated simplicity, reproducibility, and reliability.
Impact:
- Provides a reliable analytical method for quality control of Cortex Mori.
- Facilitates the identification of high-quality Sangbaipi for medicinal use.
- Contributes to the standardization of Traditional Chinese Medicine formulations.
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