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Updated: Jul 13, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Staphylococcus aureus infection complicating percutaneous coronary interventions.
Jochem W van Werkum1, Jurriën M ten Berg, H W Thijs Plokker
1Department of Cardiology, St Antonius Hospital, PO Box 2500, 3435 CM Nieuwegein, The Netherlands. woutervanwerkum@gmail.com
Staphylococcus aureus infections are rare but serious complications after percutaneous coronary interventions (PCI). Identifying risk factors like heart failure and prolonged sheath use can help prevent these infections.
Area of Science:
- Cardiology
- Infectious Diseases
- Interventional Cardiology
Background:
- Percutaneous coronary interventions (PCI) are common procedures.
- Staphylococcus aureus (S. aureus) infections can complicate PCI.
- Understanding incidence and risk factors is crucial.
Purpose of the Study:
- Determine the incidence of S. aureus infections post-PCI.
- Identify risk factors associated with these infections.
- Characterize the outcomes of S. aureus infections after PCI.
Main Methods:
- Retrospective evaluation of 7640 PCI procedures (1999-2002).
- Case-control study design to identify risk factors.
- Infection surveillance from 1 to 16 days post-PCI.
Main Results:
- 21 S. aureus infections (0.27%) occurred post-PCI.
- Increased hospital stay (24 vs 5 days) and mortality (19% vs 3%) in infected patients.
- Independent risk factors included heart failure, alcohol abuse, emergency PCI, multiple PCIs, and prolonged femoral sheath duration.
Conclusions:
- S. aureus infection is a rare but severe complication of PCI.
- Patients with identified risk factors require heightened vigilance.
- Consideration of additional precautions for high-risk patients is recommended.
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