Related Experiment Video
Updated: Jul 13, 2026

08:09
Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
Sedentary, active and athletic lifestyles: right and left ventricular long axis diastolic function
International Journal of Cardiology
|August 4, 2007
Summary
Active men aged 30-45 show higher early relaxation velocity in left ventricular long axis function compared to sedentary and athletic individuals. This key cardiac measure differs significantly between these groups.
Area of Science:
- Cardiology
- Physiology
- Sports Medicine
Background:
- Left ventricular function is crucial for cardiovascular health.
- Early relaxation velocity of the atrioventricular plane reflects diastolic function.
- Understanding how physical activity impacts cardiac mechanics is important.
Purpose of the Study:
- To investigate the early relaxation velocity of the atrioventricular plane in sedentary, active, and athletic men.
- To compare left ventricular long axis function across different physical activity levels.
Main Methods:
- Participants were men aged 30-45 years, categorized by activity level (sedentary, active, athletic).
- Measurement of early relaxation velocity of the atrioventricular plane (long axis function) of the left ventricle.
- Statistical analysis to compare velocities between groups.
Main Results:
- A significant difference in early relaxation velocity was observed at the left ventricular free wall.
- Active men exhibited a significantly greater early relaxation velocity compared to both sedentary and athletic men.
- No significant difference was noted between sedentary and athletic men.
Conclusions:
- Physical activity level influences left ventricular diastolic function.
- Active individuals demonstrate enhanced early relaxation velocity, suggesting improved cardiac mechanics.
- Sedentary and athletic groups showed similar early relaxation velocities, warranting further investigation.
Related Concept Videos
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Heart Failure II: Pathophysiology
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...

