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Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
10:58

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Published on: July 25, 2013

Combination of scoring schemes for protein docking

Philipp Heuser1, Dietmar Schomburg

  • 1Cologne University Bioinformatics Center (CUBIC), University of Cologne, Zuelpicher Str, 47, 50674 Koeln, Germany.

BMC Bioinformatics
|August 7, 2007
PubMed
Summary

This study introduces an improved protein docking algorithm using atom-specific weighting and machine learning for better binding predictions. The new method significantly enhances the accuracy of predicting near-native protein complex structures, especially for enzyme-inhibitor interactions.

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