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Related Experiment Videos

Nonlinear pulse compression in pulse-inversion fundamental imaging.

Yun-Chien Cheng1, Che-Chou Shen, Pai-Chi Li

  • 1Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan.

Ultrasonic Imaging
|August 8, 2007
PubMed
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Coded excitation in ultrasound contrast imaging can cause side-lobe artifacts, reducing contrast-to-tissue ratio. This study found coded excitation is not beneficial for pulse-inversion-based fundamental contrast detection.

Area of Science:

  • Ultrasound imaging
  • Medical physics
  • Biomedical engineering

Background:

  • Coded excitation enhances ultrasound signal-to-noise ratio with minimal microbubble destruction.
  • Pulse compression restores axial resolution lost with coded excitation.
  • Microbubble nonlinear responses pose challenges for pulse compression, causing artifacts in pulse-inversion-based (PI) fundamental imaging.

Purpose of the Study:

  • To evaluate the efficacy of pulse compression in nonlinear contrast imaging.
  • To investigate factors influencing PI fundamental generation and their impact on pulse compression.
  • To determine the benefit of coded excitation in PI fundamental contrast detection.

Main Methods:

  • In-vitro experiments and simulations were used to assess pulse compression performance.

Related Experiment Videos

  • Factors investigated included acoustic pressure and microbubble size.
  • Analysis focused on range side-lobe artifacts and contrast-to-tissue ratio (CTR) in PI fundamental imaging.

    • Main Results:

    • Acoustic pressure and bubble size significantly alter microbubble nonlinear characteristics and compression filter performance.
    • Higher acoustic pressure or microbubbles near resonance size increase range side lobes.
    • Despite increased CTR with acoustic pressure and resonance, compression reduces CTR in PI fundamental imaging due to side-lobe artifacts.

    Conclusions:

    • Coded excitation, while enhancing SNR, introduces side-lobe artifacts in nonlinear contrast imaging.
    • These artifacts degrade the contrast-to-tissue ratio after pulse compression in PI fundamental imaging.
    • The use of coded excitation is not beneficial for PI fundamental contrast detection due to these limitations.