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Comparison of prevention methods of intradialytic hypotension
1Nephrology Department, UHC Ibn Rochd, Casablanca, Morocco. hasnaa_rezki@hotmail.com
Insights
Cold dialysate and sodium ramping effectively reduce intradialytic hypotension (IDH) episodes in hemodialysis patients. These methods decrease the need for interventions, improving patient outcomes during dialysis.
Area of Science:
- Nephrology
- Cardiovascular Physiology
Background:
- Intradialytic hypotension (IDH) is a common complication during hemodialysis.
- Effective prevention strategies are crucial for patient safety and treatment efficacy.
Purpose of the Study:
- To evaluate the effectiveness of various interventions for preventing intradialytic hypotension (IDH).
- To compare standard dialysis protocols with modified sodium (Na) concentrations and dialysate temperatures.
Main Methods:
- Sixteen hemodialysis patients experiencing IDH were studied.
- Protocols included fixed Na, Na ramping, ultrafiltration alone, cold dialysate, and a combination of Na ramping and cold dialysate.
- Dialysate composition: bicarbonate, calcium 1.75 mmol/L, Na 140 mmol/L, temperature 37°C (standard).
Main Results:
- The combination of Na ramping and cold dialysate, as well as cold dialysate alone, significantly reduced IDH episodes compared to standard protocols.
- Twelve patients (78%) received two 5-hour hemodialysis sessions weekly.
- Mean interdialytic systolic blood pressure was 110.7 mmHg.
Conclusions:
- Modulating sodium concentration and using cold dialysate are effective strategies for decreasing IDH episodes.
- These interventions reduce the need for medical interventions during dialysis sessions.
Abstract:
Our study evaluates the effectiveness of the different methods of prevention of intradialytic hypotension (IDH). We studied 16 hemodialysis patients who developed IDH at Ibn Rochd University Hospital. Each patient underwent three standard sessions with cellulose diacetate dialysers and bicarbonate dialysate with calcium concentration of 1.75 mmol/L and sodium (Na) concentration of 140 mmol/L, with dialysate temperature (T) of 37 degrees C. Then the patients were subjected to five successive sessions, each time using one of the following protocols: fixed Na dialysate concentration at 144 mmol/L, Na ramping from 152 to 138 mmol/L, one hour of ultrafiltration (UF) alone followed by three hours of standard dialysis session, dialysis with standard dialysate at T o C, or a combination of Na ramping and cold dialysate. Twelve (78%) patients underwent two sessions of HD per week of five hours each. The mean systolic blood pressure (SAP) in the interdialytic period was 110.7 (100.1-125.5) mmHg; two patients underwent anti-hypertensive treatment. The combination of ramping Na and cold dialysate as well as the cold dialysate were associated with fewer episodes of hypotension in comparison with the standard dialysate. We conclude that the combination modulation of Na and cold dialysate as well as the cold dialysate are the most effective techniques to decrease the number of IDH episodes and the average number of interventions.
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