Infertility among female renal transplant recipients
S Ghazizadeh1, M Lessan-Pezeshki, M R Khatami
1Department of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran, Iran. shirin_ghazizadeh@yahoo.com
Summary
Infertility affects 13.1% of women post-kidney transplant, similar to the general population. While causes are treatable, many women show low motivation for infertility treatment.
Area of Science:
- Nephrology
- Reproductive Endocrinology
- Transplantation Medicine
Background:
- Renal allograft transplantation can impact the reproductive health of women.
- Evaluating reproductive system function is crucial for post-transplant care.
Purpose of the Study:
- To assess the prevalence and causes of infertility in women who have undergone kidney transplantation.
- To understand treatment seeking behavior for infertility in this population.
Main Methods:
- A study of 122 women with renal allografts was conducted.
- Reproductive system evaluation included assessment of menopausal status, marital status, and infertility definitions.
- Treatment outcomes and reasons for treatment refusal were recorded.
Main Results:
- 13.1% of married, reproductive-aged women (76 total) experienced infertility.
- Causes included male factor (3), ovulatory problems (3), and undefined (4).
- Only 6 patients received treatment (ovulation induction +/- IUI), with 2 achieving pregnancy; 4 refused treatment due to various reasons.
Conclusions:
- Infertility prevalence in female renal transplant recipients mirrors the general population.
- Most infertility causes are treatable, yet motivation for treatment appears low in this cohort.
- Further research into barriers to infertility treatment in transplant recipients is warranted.
Related Concept Videos
01:26Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
01:28Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
01:28Infertility in Females
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of endometrial...
Endometriosis, a condition characterized by abnormal growth of endometrial...
01:16Kidney Transplant III: Nursing Management
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
01:23Infertility in Males
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
01:11Renal Failure: Dose Adjustments
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...