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Extending the enteric nervous system.

Andrea Sbarbati1, Francesco Osculati

  • 1Department of Morphological and Biomedical Science, Section of Anatomy and Histology, University of Verona, Medical Faculty, Strada Le Grazie 8, 37134, Verona, Italy. andrea.sbarbati@univr.it

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|August 8, 2007
PubMed
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The lingual enteric nervous system (LENS) acts as a "chemical eye," analyzing food before ingestion. This rostral portion of the autonomic nervous system modulates digestive functions and offers a model for studying enteric nervous system connectivity.

Area of Science:

  • Neuroscience
  • Gastroenterology
  • Autonomic Nervous System Research

Background:

  • The enteric nervous system (ENS) traditionally refers to the neural network within the digestive tract.
  • The autonomic nervous system (ANS) controls involuntary bodily functions.
  • The gustatory and trigeminal systems provide sensory input to the oral cavity.

Purpose of the Study:

  • To review evidence supporting the concept of a lingual enteric nervous system (LENS).
  • To define the LENS as the most rostral part of the ENS.
  • To explore the LENS's role in sensory analysis and modulation of digestive functions.

Main Methods:

  • Review of existing scientific literature and evidence.
  • Analysis of neuroanatomical and functional connections.

Related Experiment Videos

  • Conceptual definition based on integrated data.

    • Main Results:

    • Lingual components of the autonomic system are proposed as the rostral ENS (LENS).
    • LENS features massive sensory input from gustatory and trigeminal fibers.
    • LENS neurons regulate secretion and vasomotility, influencing digestive and respiratory systems.

    Conclusions:

    • The LENS functions as a "chemical eye" analyzing food prior to ingestion.
    • It modulates distal organ activity via annexed glands and neural connections.
    • The LENS model aids in understanding ENS autonomy and gustatory system influence on digestion.