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Updated: Jul 13, 2026

Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors
Published on: July 16, 2012
[Endocrine disorders in HCV infection]
Paweł Piszko1, Katarzyna Fleischer, Krzysztof Simon
1Katedra i Klinika Chorób Zakaźnych, Chorób Watroby i Nabytych Niedoborów Odpomościowych, Akademii Medycznej we Wrocławiu. pawelp@generacja.net
Abstract:
Thyroid disorders and diabetes mellitus t. II are the most common disorders observed among of endocrine extrahepatic manifestations of HCV infection. The mechanism of this disorders is still unclear. Two main hypothesis are considered: primary cytopathic effect of virus and secondary-induced autoimmunity. The ability of HCV to infect central nervous system cells seems to be significant in the hypothalamus--epiphysis--axis dysfunction. Further clinical researches are awaited in order to explain phenomenon mentioned above.
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