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Updated: Jul 13, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
[Management of renal complications during primary angioplasty]
Giancarlo Marenzi1, Ivana Marana, Antonio Bartorelli
1Centro Cardiologico Monzino, I.R.C.C.S., Istituto di Cardiologia, Università, Milano. giancarlo.marenzi@ccfm.it
Insights
Primary angioplasty is key for ST-elevation myocardial infarction, but risks contrast-induced nephropathy. This review covers kidney issues in heart attacks and prevention strategies.
Area of Science:
- Cardiology
- Nephrology
- Interventional Cardiology
Context:
- ST-elevation acute myocardial infarction (STEMI) management.
- Primary angioplasty as reperfusion therapy.
- Contrast-induced nephropathy (CIN) as a complication.
Purpose:
- Summarize the clinical and prognostic relevance of renal insufficiency and CIN in STEMI.
- Highlight current evidence on CIN in acute myocardial infarction.
- Emphasize novel preventive strategies for kidney protection.
Summary:
- Primary angioplasty is optimal for STEMI reperfusion but carries a high risk of CIN.
- CIN is a renal complication significantly increasing morbidity and mortality in STEMI patients.
- The paper reviews the impact of renal insufficiency and CIN and discusses protective measures.
Impact:
- Informs clinicians about the risks of CIN in STEMI patients undergoing angioplasty.
- Provides an overview of current evidence regarding renal complications in acute myocardial infarction.
- Highlights the need for and potential of preventive strategies to improve patient outcomes.
Abstract:
Primary angioplasty represents the best strategy for myocardial reperfusion in ST-elevation acute myocardial infarction. However, it is associated with a high risk of developing contrast-induced nephropathy, a renal complication coupled with markedly increased morbidity and mortality rates. This paper summarizes, on the current evidence available, the clinical and prognostic relevance of renal insufficiency and contrast-induced nephropathy in acute myocardial infarction, and emphasizes new possible preventive strategies for kidney protection in this clinical setting.
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