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Updated: Jul 13, 2026

A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells
Published on: September 28, 2019
Evaluation of ganglion cysts using vastly undersampled isotropic projection reconstruction (VIPR)
Kimberly K Amrami1, Nicholas M Desy, David W Stanley
1Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA. amrami.kimberly@mayo.edu
Abstract:
For some atypical para-articular ganglia, the presence of a joint connection is highly controversial. The proper preoperative diagnosis and identification of this joint connection for ganglion cysts is important for patient treatment and outcome. MRI is the imaging modality of choice when evaluating such lesions, but the detection of subtle joint connections remains difficult with conventional MR protocols. We investigated the utility of a steady-state free-precession acquisition with isotropic high resolution using the vastly undersampled isotropic projection reconstruction (VIPR) pulse sequence to determine if joint connections for ganglion cysts could be seen more effectively, using the knee region as a model. We evaluated four patients: two with peroneal intraneural ganglion cysts, one with adventitial cystic disease of the popliteal artery, and one patient with a more typical extraneural (intramuscular) cyst. Both conventional MR and VIPR techniques were used. In our clinical experience, we found VIPR to be superior to conventional MR techniques in detecting and depicting joint connections in typical and atypical ganglion cysts around the knee.
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