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Progesterone receptor expression in human cervix uteri
1Department of Pathomorphology, Institute of Obstetrics and Gynecology, Medical School of Warsaw, Poland.
Zentralblatt Fur Pathologie
|January 1, 1991
Abstract:
Progesterone receptor (PR) expression was studied in human cervix uteri from 21 cases. The study was performed on fresh frozen material with application of mouse anti-rabbit PR antibody and the immunoperoxidase method. Most cervical PR-s were present in the glandular epithelium and in smooth muscle cells. The results suggest that PR expression in the cervical glands is hormone-dependent; it was strongest in the presence of estrogen-stimulated endometrium, weaker with progesterone stimulation and absent in atrophy. The ectocervical epithelium contained relatively few progesterone receptors.