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Dolosigranulum pigrum causing nosocomial pneumonia and septicemia
Hervé Lécuyer1, Juliette Audibert, Astrid Bobigny
1Service de Microbiologie, AP-HP, Hôpital Européen Georges Pompidou, 20 rue Leblanc, 75908 Paris Cedex 15, France.
Journal of Clinical Microbiology
|August 10, 2007
Summary
A rare bacterium, Dolosigranulum pigrum, caused hospital-acquired pneumonia and sepsis in a weakened patient. This opportunistic pathogen was identified using 16S rRNA gene sequencing.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Case Reports
Background:
- Nosocomial infections pose significant challenges in healthcare settings.
- Opportunistic pathogens can cause severe disease in debilitated individuals.
- Dolosigranulum pigrum is a rarely reported gram-positive bacterium.
Observation:
- A case of non-ventilator-associated nosocomial pneumonia and septicemia was observed.
- The patient was debilitated, increasing susceptibility to infection.
- The causative agent was isolated from bronchoalveolar lavage fluid and blood cultures.
Findings:
- Dolosigranulum pigrum was identified as the causative pathogen.
- 16S rRNA gene sequencing confirmed the identification of D. pigrum.
- This case highlights D. pigrum as a potential cause of severe nosocomial infections.
Implications:
- Awareness of D. pigrum as a potential opportunistic pathogen is crucial for clinicians.
- Accurate and timely identification of rare pathogens is essential for effective treatment.
- Further research may be warranted to understand the pathogenicity and treatment of D. pigrum infections.
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