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[Nutritional pathway for autologous stem cell transplantation]
Takashi Aoyama1, Osamu Imataki, Naomi Inoue
1Division of Nutrition, Shizuoka Cancer Center.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|August 10, 2007
Summary
A new nutritional pathway for autologous stem cell transplantation (SCT) improved oral intake and reduced weight loss in patients with malignant lymphoma and multiple myeloma. This dietary intervention shows promise for enhancing patient recovery post-SCT.
Area of Science:
- Oncology
- Hematology
- Nutrition Science
Context:
- Autologous stem cell transplantation (SCT) is a critical treatment for malignant lymphoma and multiple myeloma.
- Nutritional status significantly impacts patient outcomes during and after SCT.
- Standardized nutritional support protocols are essential for optimizing SCT recovery.
Purpose:
- To develop and evaluate an original nutritional pathway for autologous SCT patients.
- To assess the impact of a dietitian-led nutritional intervention on patient outcomes.
- To compare clinical data between patients with and without the nutritional pathway.
Summary:
- A nutritional pathway was implemented for 37 patients undergoing autologous SCT.
- Ten patients received targeted nutritional support, with dietitian-led assessments.
- Compared to a control group (n=27), the intervention group (n=10) showed significantly increased oral intake at day 14 (1,440 kcal vs. 1,038 kcal) and reduced body weight loss (10% vs. 52%).
Impact:
- The nutritional pathway led to improved oral caloric intake and reduced significant weight loss in SCT patients.
- A 3-day reduction in central venous catheter (CVC) insertion duration was observed.
- The findings suggest the efficacy of a structured nutritional pathway in enhancing recovery and potentially reducing complications following autologous SCT.
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