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Updated: Jul 13, 2026
Layer-by-layer Collagen Deposition in Microfluidic Devices for Microtissue Stabilization
Published on: September 29, 2015
Physicochemical properties of succinylated calfskin pepsin-solubilized collagen
Zhongkai Zhang1, Wentao Liu, Dong Li
1The Key Laboratory of Leather Chemistry and Engineering of the Ministry of Education, Sichuan University, Chengdu, PR China.
Abstract:
Some physicochemical properties of calfskin pepsin-solubilized collagen (PSC) and succinylated PSC (SPSC) were compared. The amino acid profile remained significantly unchanged. Sodium dodecylsulphate-polyacrylamide gel electrophoresis showed that subunits of SPSC migrated less than those of PSC. The denaturation temperatures of PSC and SPSC were 38.4 degrees C and 34.7 degrees C respectively. Succinylation slightly altered the triple-helical conformation of collagen, as determined by circular dichroism.
