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Updated: Jul 13, 2026

An Inverse Analysis Approach to the Characterization of Chemical Transport in Paints
Published on: August 29, 2014
Acute effects of some volatile organic compounds emitted from water-based paints
Lena Ernstgård1, Agneta Löf, Gunilla Wieslander
1Work Environment Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Lena.Ernstgard@ki.se
Objective:
Acute effects during controlled exposure to some of the volatile organic compounds emitted from water-based paints were evaluated.
Methods:
Healthy volunteers (10 atopics, 10 nonatopics, and 10 painters) were exposed to a mixture of propyleneglycol, texanol, diethyleneglycol monoethylether, diethyleneglycol monobutyl ether, and dipropyleneglycol monomethyl ether at a total concentration of 35 mg/m3 (G), a mixture of G and ammonia (15 mg/m3) (GA), and clean air (C).
Results:
Subjective ratings of irritation in eyes, nose, throat, and dyspnea were significantly higher during the G and GA conditions, when compared with during the C condition. Nasal mucosal swelling was observed after G but not after GA exposure. No effects of the exposure on the pulmonary function, markers of inflammation in nasal lavages, and renal function in urine were seen.
Conclusion:
Exposure to G and GA caused mild irritation in eyes, nose, and airways.
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