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Cardiovascular risk factors in Nigerians with systemic hypertension
K M Karaye1, B N Okeahialam, S S Wali
1Department of Medicine, Aminu Kano Teaching Hospital, Kano, Nigeria. kkaraye@yahoo.co.uk
Insights
Hypertension significantly increases cardiovascular risk, with high prevalence of risk factors and target organ damage, particularly in treated patients. Increased Body Mass Index and Left Ventricular Hypertrophy were common findings.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Hypertension is a primary risk factor for cardiovascular disease.
- It often coexists with other risk factors, elevating absolute cardiovascular risk.
- Understanding these coexisting factors and their impact is crucial for patient management.
Purpose of the Study:
- To assess cardiovascular risk factors in hypertensive patients compared to controls.
- To evaluate target organ damage in hypertensive individuals.
- To determine the absolute cardiovascular risk among hypertensive patients.
Main Methods:
- A case-control study was conducted at Aminu Kano Teaching Hospital, Nigeria.
- Three groups (treated hypertensives, untreated hypertensives, controls), each with 70 participants, were matched for age and sex.
- Simple random sampling was employed for patient selection.
Main Results:
- Increased Body Mass Index was the most prevalent risk factor, significantly higher in treated hypertensives (70%) than untreated (45.7%) and controls (44.3%).
- Left Ventricular Hypertrophy was the most common target organ damage (54.3% treated, 42.9% untreated).
- Very high cardiovascular risk was observed in 75.6% of treated and 68.5% of untreated hypertensives.
Conclusions:
- Hypertensive patients exhibit a high prevalence of cardiovascular risk factors and target organ damage even before treatment.
- These conditions are more pronounced in treated hypertensive individuals.
- The findings highlight the need for comprehensive management strategies for hypertension.
Background:
Hypertension is the commonest risk factor for cardiovascular disease, and it frequently coexists together with other risk factors, thereby increasing the absolute cardiovascular risk. This study is primarily aimed at assessing cardiovascular risk factors in patients with hypertension in comparison with controls. It is also aimed at assessing target organ damage and absolute cardiovascular risk among the hypertensives.
Study Design:
The study was case-control in design, conducted at the General outpatient and Cardiology Clinics of Aminu Kano Teaching Hospital, Kano, Nigeria. Three groups of patients (treated hypertensives, untreated hypertensives and controls), each 70 in number, were matched for age and sex. Patients were selected by balloting, using simple random sampling method.
Results:
The most prevalent cardiovascular risk factor was Increased Body Mass Index, which was significantly more prevalent among treated (70%) than untreated (45.7%) hypertensives and controls (44.3%). Left Ventricular Hypertrophy was the most prevalent Target Organ Damage, found in 54.3% of treated and 42.9% of untreated hypertensives, and 0% of controls. Very high cardiovascular risk was detected in 75.6% of treated and 68.5% of untreated hypertensives.
Conclusion:
Even before the commencement of treatment, hypertenisves had high prevalence of cardiovascular risk factors and evidence of target organ damage. These were more pronounced in treated hypertensives. The basis and prognosis are discussed.
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