Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Eye Care Professionals' Knowledge, Attitude and Practice (KAP) on Myopia Management Approach: A Global Review.

Kathmandu University medical journal (KUMJ)·2026
Same author

A data-light composite climate resilience index reveals superior drought resilience of millets in rainfed agroecosystems.

Scientific reports·2026
Same author

Epithelial ingrowth post small incision lenticule extraction: CIRCLE software to the rescue.

Medical journal, Armed Forces India·2026
Same author

Telemedicine in Pediatric Diabetes Care: The Way Forward?

Indian pediatrics·2025
Same author

Analytical derivation of optimal irrigation water depth for efficient irrigation scheduling.

Environmental monitoring and assessment·2024
Same author

Bacteriology of endotracheal tube biofilms and antibiotic resistance: a systematic review.

The Journal of hospital infection·2024

Related Experiment Video

Updated: Jul 13, 2026

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
12:24

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Published on: June 20, 2014

Myocardial dysfunction in rheumatic carditis--does it really exist?

T K Mishra1, N K Mohanty, S K Mishra

  • 1Department of Cardiology, MKCG Medical College and Hospital, Berhampur 760 004, Orissa.

The Journal of the Association of Physicians of India
|August 19, 2007
PubMed
Summary

This study found no evidence of myocardial dysfunction or elevated cardiac troponin I in acute rheumatic fever patients with heart failure. Myocardial involvement does not appear to significantly contribute to heart failure in rheumatic carditis.

More Related Videos

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
10:21

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Published on: June 14, 2016

Related Experiment Videos

Last Updated: Jul 13, 2026

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
12:24

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Published on: June 20, 2014

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
10:21

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Published on: June 14, 2016

Area of Science:

  • Cardiology
  • Pediatrics
  • Rheumatology

Background:

  • Acute rheumatic fever (ARF) remains a significant health concern, particularly in developing nations, affecting millions of children.
  • Rheumatic carditis, a complication of ARF, can lead to heart failure, but the underlying mechanisms are not fully understood.
  • Limited research exists on the role of myocardial dysfunction in the development of heart failure among patients with rheumatic carditis.

Purpose of the Study:

  • To investigate the potential role of myocardial dysfunction in the genesis of heart failure in patients diagnosed with rheumatic carditis.
  • To assess echocardiographic parameters and cardiac troponin I levels in ARF patients with varying degrees of carditis.
  • To determine if myocardial damage contributes to heart failure in the context of rheumatic carditis.

Main Methods:

  • A prospective study involving 108 consecutive patients with ARF.
  • Echocardiography was performed to evaluate left ventricular dimensions and ejection fraction.
  • Blood levels of cardiac troponin I were measured as a biomarker for myocardial damage.
  • Patients were categorized into three groups: no carditis, first attack of carditis, and recurrent carditis.

Main Results:

  • Left ventricular dimensions were larger in patients with first or recurrent carditis compared to those without carditis.
  • Left ventricular ejection fraction did not significantly differ across the groups.
  • Heart failure was more prevalent in patients with recurrent carditis (60.6%) than in those with a first attack (37.7%).
  • The majority of heart failure patients (75.7%) had normal ejection fractions; reduced ejection fraction was observed in a minority of patients with heart failure.
  • Mean cardiac troponin I levels were comparable across all three groups, indicating no significant myocardial damage.
  • Low ejection fraction was associated with hemodynamically significant regurgitant valvular lesions.

Conclusions:

  • The study found no significant echocardiographic abnormalities or elevated cardiac troponin I levels indicative of substantial myocardial involvement during acute rheumatic fever.
  • These findings suggest that myocardial dysfunction does not play a major role in the development of heart failure in patients suffering from rheumatic carditis.
  • The primary drivers of heart failure in rheumatic carditis appear to be related to valvular lesions rather than direct myocardial damage from ARF.