Related Experiment Video
Updated: Jul 13, 2026
13:19
Chemical Triphosphorylation of Oligonucleotides
Published on: June 2, 2022
Adenosine residues in the template do not block spontaneous replication steps of RNA
Stephanie R Vogel1, Clemens Richert
1Institute for Organic Chemistry, University of Karlsruhe (TH), 76131 Karlsruhe, Germany.
Chemical Communications (Cambridge, England)
|August 19, 2007
Abstract:
Sub-freezing temperatures, azabenzotriazolide activation, multiple monomer addition, and helper displacement help to overcome what seemed like an intrinsic block of adenine-templated RNA replication steps in the absence of enzymes.
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