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Immediate peri-operative memory.

M M Ghoneim1, R I Block

  • 1Department of Anesthesia, University of Iowa, Iowa City, IA 52244, USA. mohamed.ghoneim@uiowa.edu

Acta Anaesthesiologica Scandinavica
|August 19, 2007
PubMed
Summary
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Post-surgery, patients experienced severe memory impairment for neutral stimuli, but retrograde amnesia was not detected. Memory for peri-operative events was not better than verbal memory.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Anesthesiology

Background:

  • Peri-operative amnesia, both anterograde and retrograde, is poorly understood.
  • Assessing memory for real-life events during the peri-operative period is challenging.

Purpose of the Study:

  • To investigate the presence of anterograde and retrograde amnesias in patients undergoing general anesthesia and surgery.
  • To compare memory for peri-operative events with verbal memory recall.

Main Methods:

  • 40 patients under general anesthesia and 19 matched controls participated.
  • Word lists were presented in holding, operating, and recovery rooms; memory tested via recall and recognition.
  • A questionnaire assessed memory for events occurring on the day of surgery.

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Main Results:

  • Significant impairment in word recall and recognition was observed in the recovery room.
  • No significant difference in memory decline between patients and controls from holding to operating room.
  • No significant differences in recognition of peri-operative events between groups.

Conclusions:

  • Retrograde amnesia was not detected in the study.
  • Severe impairment of memory for neutral stimuli occurred in the recovery room.
  • The utilized events questionnaire was found to be insensitive for assessing peri-operative memory.