Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

Imaging Studies III: Computed Tomography

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

Ultrasonography

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...

Imaging Studies II: Ultrasonography

Imaging Studies II: Ultrasonography

IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...

Imaging Biological Samples with Optical Microscopy

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

Ultrasound II: Endoscopic Ultrasound and FibroScan

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Activatable smart contrast agents for photoacoustic imaging.

Smart molecules : open access·2026

Same author

Multiscale photoacoustic imaging of stroke in preclinical models and future directions toward clinical translation [Invited].

Biomedical optics express·2026

Same author

Pulse Repetition Frequency Tuned Low-Intensity Focused Ultrasound Neuromodulation for Tibial Nerve Targeted Bladder Function Modulation.

IEEE transactions on bio-medical engineering·2026

Same author

Introduction to the feature issue Photoacoustic Imaging and Sensing: Beyond Fundamentals to Translation.

Biomedical optics express·2026

Same author

Fully integrated photoacoustic microscopy for multi-scale and longitudinal imaging in translational biomedical applications.

Biomedical optics express·2026

Same author

Ultrasonic modulation of brain glymphatic transport: from observations to theranostic applications.

Cancer drug resistance (Alhambra, Calif.)·2026

Search research articles

Related Experiment Video

Updated: Jul 13, 2026

Multispectral Optoacoustic Tomography for Functional Imaging in Vascular Research

Multispectral Optoacoustic Tomography for Functional Imaging in Vascular Research

Published on: June 8, 2022

Imaging optically scattering objects with ultrasound-modulated optical tomography.

Sri-Rajasekhar Kothapalli¹, Sava Sakadzić, Chulhong Kim

¹Department of Biomedical Engineering, Optical Imaging Laboratory, Washington University in St. Louis, One Brookings Drive, St. Louis, MO 63130-4899, USA.

|August 19, 2007

Summary

This study demonstrates ultrasound-modulated optical tomography (UOT) can image objects based on their scattering properties. Image contrast in UOT is achievable by exploiting differences in optical scattering coefficients.

More Related Videos

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

Published on: November 4, 2014

Related Experiment Videos

Last Updated: Jul 13, 2026

Multispectral Optoacoustic Tomography for Functional Imaging in Vascular Research

Multispectral Optoacoustic Tomography for Functional Imaging in Vascular Research

Published on: June 8, 2022

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

Published on: November 4, 2014

Area of Science:

Biomedical Optics
Medical Imaging
Photonics

Background:

Ultrasound-modulated optical tomography (UOT) is an emerging imaging technique.
Previous UOT studies focused on optical absorption contrast.

Purpose of the Study:

To demonstrate the feasibility of UOT for imaging objects with varying optical scattering coefficients.
To investigate the relationship between scattering properties and image contrast in UOT.

Main Methods:

Utilized ultrasound-modulated optical tomography (UOT).
Employed a CCD-based speckle contrast detection scheme.
Validated experimental results with Monte Carlo simulations and analytical calculations.

Main Results:

Successfully imaged objects based on differences in their optical scattering coefficients.
Image contrast was found to be dependent on the scattering coefficient difference between the object and the surrounding medium.
Spatial resolution was observed to be influenced by ultrasound parameters.

Conclusions:

UOT is a feasible method for imaging scattering-based contrast.
This technique expands the capabilities of UOT beyond absorption contrast imaging.
The findings support the development of UOT for diverse biomedical imaging applications.