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Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
Multivariate risk assessment and risk score cards in hypertension
Giuliano Tocci1, Valentina Valenti, Sebastiamo Sciarretta
1Cardiology, II Faculty of Medicine, University of Rome La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Insights
Hypertension management should shift from focusing solely on blood pressure to a comprehensive cardiovascular risk assessment. This approach is crucial for reducing cardiovascular events in hypertensive patients.
Area of Science:
- Cardiology
- Preventive Medicine
- Public Health
Background:
- Cardiovascular disease is a leading cause of death globally, with hypertension-related events affecting millions annually.
- Hypertension significantly increases long-term cardiovascular event risk, making blood pressure management a key preventive strategy.
- Current hypertension treatment often focuses narrowly on blood pressure, neglecting the broader cardiovascular risk profile.
Purpose of the Study:
- To advocate for a shift in hypertension management strategies.
- To emphasize the importance of a comprehensive cardiovascular risk evaluation in hypertensive patients.
- To reduce cardiovascular morbidity and mortality through integrated patient management.
Main Methods:
- Review of current hypertension management practices.
- Analysis of the multifactorial pathophysiology of hypertension and its associated risks.
- Proposal of a comprehensive risk evaluation model for hypertensive patients.
Main Results:
- General practitioners frequently manage hypertension by targeting only blood pressure levels.
- An integrated approach considering lifestyle, medications, and comorbidities is essential for effective hypertension management.
- A comprehensive cardiovascular risk assessment is more effective than single-factor management for reducing adverse events.
Conclusions:
- Modern cardiovascular prevention in hypertensive patients requires a move from single-risk-factor management to a holistic risk evaluation.
- Defining and managing global cardiovascular risk is paramount for high-risk hypertensive individuals.
- A comprehensive approach is vital for reducing cardiovascular morbidity and mortality in both the general and hypertensive populations.
Abstract:
Cardiovascular disease represents the leading cause of morbidity and mortality in Western countries, and hypertension-related cardiovascular events affect about 37 million people per year, worldwide. In this perspective, hypertensive patients are at increased risk to experience cardiovascular events during life-long period, and treatment of high blood pressure represents one of the most effective strategies to reduce global cardiovascular risk. However, due to its multifactorial pathophysiology and its frequent association with other relevant risk factors and clinical conditions, treatment of hypertension requires an integrated approach, including life-style measures, antihypertensive drugs and other therapies. Yet, worldwide general practitioners continue to focus their attention on the management of a single risk factor, eg, blood pressure, rather than to global cardiovascular risk profile. In this view, modem strategies of cardiovascular prevention in hypertensive patients should move from a single risk factor based approach toward a more comprehensive risk evaluation in the individual patient. In other words, it is important to define the global cardiovascular risk to manage hypertensive patients at high-risk, rather than to focus on the high level of a single risk factor, for reducing cardiovascular morbidity and mortality in the general population, as well as in hypertensive population.
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