Nonnative protein polymers: structure, morphology, and relation to nucleation and growth

William F Weiss1, Travis K Hodgdon, Eric W Kaler

  • 1Department of Chemical Engineering, University of Delaware, Newark, Delaware, USA.

Biophysical Journal
|August 21, 2007
PubMed
Summary

Thermally induced protein aggregates form linear polymer chains. This study characterizes their structure and kinetics, revealing a nucleated polymerization process for alpha-chymotrypsinogen A.

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