Related Experiment Video
Updated: Jul 13, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio
Published on: August 24, 2013
Prospect of manufacturing and design based on physiological polymorphism
Masashi Nakamura1, Teruhiko Fuwa, Kaoru Inoue
1Division of Forest and Biomaterials Science, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto 606- 8502, Japan. nakamasa@kais.kyoto-u.ac.jp
Manufacturing and design must consider human physiological polymorphism for user satisfaction. This approach moves beyond average data to embrace individual variations for better product development.
Area of Science:
- Human-centered design
- Physiological anthropology
- Manufacturing innovation
Background:
- Modern manufacturing demands user satisfaction alongside cost-effectiveness.
- Rapid technological shifts necessitate adaptive design strategies.
- Current reliance on average physiological data limits product personalization.
Purpose of the Study:
- To introduce the concept of manufacturing and design based on physiological polymorphism.
- To explore applications of this concept across diverse fields.
- To propose a procedure for implementing polymorphic design.
Main Methods:
- Reviewing the limitations of average-value interpretation in physiological data.
- Applying principles of physiological anthropology to design.
- Discussing methodologies across seven application areas.
Main Results:
- Concept of manufacturing and design based on physiological polymorphism is established.
- Identified seven key fields for application: welfare equipment, clothing, artificial tissue, sporting gear, furniture, building materials, and human interface.
- Developed a procedural framework for polymorphic design.
Conclusions:
- Physiological polymorphism is crucial for creating user-satisfying products.
- A shift from average-based design to polymorphic design is essential for future manufacturing.
- The proposed framework enables tailored product development considering human variability.
Related Concept Videos
Principles of Pharmacogenetics: Types of Genetic Variants
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu
Pharmacogenomics: Identification of New Drug Targets
Pharmacogenetics of Drug Metabolism: Overview
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Model Approaches for Pharmacokinetic Data: Physiological Models

