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The IKK inhibitor BMS-345541 affects multiple mitotic cell cycle transitions

Hana Blazkova1, Conrad von Schubert, Keith Mikule

  • 1Division of Molecular Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Cell Cycle (Georgetown, Tex.)
|August 21, 2007
PubMed
Summary

The IkappaB kinase (IKK) inhibitor BMS-345541 disrupts mitosis, affecting cell cycle progression and cytokinesis. This reveals a novel role for IKK in regulating cell division, potentially impacting cancer therapeutics.

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