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Updated: Jul 13, 2026

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

Structural requirements for uptake and recognition of CpG oligonucleotides

Klaus Heeg1, Alexander Dalpke, Mirjam Peter

  • 1Department of Hygiene and Medical Microbiology, Institute of Hygiene, University of Heidelberg, Im Neuenheimer Feld 324, D-69120 Heidelberg, Germany. klaus.heeg@med.uni-heidelberg.de

International Journal of Medical Microbiology : IJMM
|August 21, 2007
PubMed
Summary

Bacterial CpG DNA, recognized by Toll-like receptor 9 (TLR9), enhances immune responses. Modifications to CpG DNA improve its therapeutic potential for vaccines, cancer, and allergy treatments.

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