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Updated: Jul 13, 2026

Transcranial Direct Current Stimulation (tDCS) of Wernicke's and Broca's Areas in Studies of Language Learning and Word Acquisition
Published on: July 13, 2019
'Does Broca's area exist?' Christofredo Jakob's 1906 response to Pierre Marie's holistic stance
Kyrana Tsapkini1, Ana B Vivas, Lazaros C Triarhou
1Department of Psychology, Aristotelian University, Thessaloniki 54124, Greece.
Abstract:
In 1906, Pierre Marie triggered a heated controversy and an exchange of articles with Jules Déjerine over the localization of language functions in the human brain. The debate spread internationally. One of the timeliest responses, that appeared in print 1 month after Marie's paper, came from Christofredo Jakob, a Bavarian-born neuropathologist working in Buenos Aires. The present study comprises an English translation of Jakob's 1906 paper and a discussion of Jakob's ideas on the localizationist-holistic approach regarding the role of Broca's area. This issue is still at the core of scientific debate in the light of current neuropsychological and neuroimaging findings.
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