Effects of acute exposure to a 1439 MHz electromagnetic field on the microcirculatory parameters in rat brain
Hiroshi Masuda1, Akira Ushiyama, Shogo Hirota
1Department of Environmental Health, National Institute of Public Health, Wako-shi, Saitama, Japan. msd@niph.go.jp
Unlabelled:
THE AIM of this study was to determine the potential of radio-frequency electromagnetic fields (RF-EMF) to affect cerebral microcirculation, including blood-brain barrier function, in rat brain.
Materials And Methods:
The head of the rat was exposed for 10 min to 1439 MHz RF-EMF having three intensity doses: 0.6, 2.4, 4.8 W/kg of brain averaged specific absorption rate (BASAR). Four microcirculatory parameters: blood-brain barrier permeability, leukocyte behavior, plasma velocity, and vessel diameter were measured before and after RF-EMF exposure using a closed cranial window method.
Results:
No extravasation of intravenously injected dyes from pial venules was found at any BASAR level. No significant changes in the number of endothelial-adhering leukocytes after exposure were found. The hemodynamics indicated that the plasma velocities and vessel diameters remained constant within the physiological range throughout each exposure.
Conclusion:
These findings suggest that there were no effects on the cerebral microcirculation under the given RF-EMF exposure conditions.
