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Published on: October 10, 2025
Fluoroscopic-guided intradiscal oxygen-ozone injection therapy for thoracolumbar intervertebral disc herniations in
Hyun-Jung Han1, Joon-Young Kim, Ha-Young Jang
1Department of Veterinary Surgery, College of Veterinary Medicine, Chungbuk National University, Chungbuk, 361-763, Republic of Korea.
Background:
To investigate the effect of oxygen-ozone (O2-O3) injection on thoracolumbar intervertebral disc herniation (IVDH) in dogs.
Materials And Methods:
Ten herniated discs of five dogs were treated with percutaneous injection of an O2-O3 gas mixture with O3 concentration of 32 microg/microl intradiscally (1.5-2 microl) under fluoroscopy guidance.
Results:
Five weeks after treatment, the mean size of herniated discs was measured by computed tomography and showed significant reduction of disc volumes in all animals (8.8%+/-3.82%). The degree of shrinkage was negatively linearly correlated with disc mineralization (correlation coefficient=-0.636) and statistically significant at p<0.05. All five dogs regained their gait function and none recurred.
Conclusion:
We conclude that intradiscal O2-O3 injection can decompress affected discs by disc shrinkage.
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