Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The 'Institutional Lottery': Institutional variation in the processes involved in accessing late abortion in Victoria, Australia.

Women's studies international forum·2024

Same author

The ethics of natural immunity exemptions to vaccine mandates: the Supreme Court petition.

Journal of medical ethics·2024

Same author

World Athletics regulations unfairly affect female athletes with differences in sex development.

Journal of the philosophy of sport·2024

Same author

Decentralising the Self - Ethical Considerations in Utilizing Decentralised Web Technology for Direct Brain Interfaces.

Science and engineering ethics·2024

Same author

On the prospects of longtermism.

Bioethics·2024

Same author

Australian public perspectives on genomic newborn screening: which conditions should be included?

Human genomics·2024

Search research articles

Related Experiment Video

Updated: Jul 12, 2026

Reprogramming Primary Amniotic Fluid and Membrane Cells to Pluripotency in Xeno-free Conditions

Reprogramming Primary Amniotic Fluid and Membrane Cells to Pluripotency in Xeno-free Conditions

Published on: November 27, 2017

Towards a global human embryonic stem cell bank.

Jason P Lott¹, Julian Savulescu

¹School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. jason.lott@gmail.com

The American Journal of Bioethics : AJOB

|August 22, 2007

Summary

Human embryonic stem cell (hESC) technology offers a solution to organ shortages by regenerating tissues. Creating a global hESC bank addresses immunological challenges and improves organ allocation for marginalized groups.

More Related Videos

Derivation of Human Embryonic Stem Cells by Immunosurgery

Derivation of Human Embryonic Stem Cells by Immunosurgery

Published on: December 13, 2007

Related Experiment Videos

Last Updated: Jul 12, 2026

Reprogramming Primary Amniotic Fluid and Membrane Cells to Pluripotency in Xeno-free Conditions

Reprogramming Primary Amniotic Fluid and Membrane Cells to Pluripotency in Xeno-free Conditions

Published on: November 27, 2017

Derivation of Human Embryonic Stem Cells by Immunosurgery

Derivation of Human Embryonic Stem Cells by Immunosurgery

Published on: December 13, 2007

Area of Science:

Regenerative Medicine
Immunology
Bioethics

Background:

A significant organ shortage exists, limiting treatment options for many diseases.
Human embryonic stem cell (hESC) technology shows promise for tissue regeneration.
Existing hESC applications face immunological hurdles for widespread use.

Purpose of the Study:

To address immunological challenges in hESC-based therapies.
To propose strategies for deriving widely immunocompatible hESC lines.
To advocate for a global hESC bank to improve organ transplantation equity.

Main Methods:

Review of current immunological barriers in transplantation.
Analysis of strategies for generating diverse hESC lines.
Ethical and practical considerations for establishing a global hESC bank.

Main Results:

Deriving hESC lines from diverse embryos can enhance immunocompatibility.
A global hESC bank could mitigate organ allocation disparities.
Recommendations for ethical construction and management of an hESC bank are provided.

Conclusions:

A global hESC bank is crucial for overcoming transplantation barriers.
This approach can enhance equitable access to regenerative therapies.
Strategic development of hESC banks offers a viable solution to organ shortages.