Related Experiment Videos
[Association between serum adiponectin and mean blood pressure]
Xin-Li Li1, Min Tong, Qiong Xu
1Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. xinli3267@yeah.net
Objective:
To investigate the relationship between serum adiponectin and mean blood pressure (BP).
Methods:
A total of 187 subjects were divided into four groups according to BP levels: optimal blood pressure group (n = 38), high normal blood pressure group (n = 50), treated hypertension group (n = 54) and untreated hypertension group (n = 45). Serum adiponectin and microalbuminuria were detected by radioimmunology assay. Insulin resistant index defined as HOMA-IR and urinary concentration of microalbuminuria/urinary concentration of creatinine defined as albumin creatinine ratio (ACR) were calculated.
Results:
(1) Serum adiponectin decreased in proportion to BP increase and the serum adiponectin level was significantly higher in treated hypertension group than untreated hypertension group. (2) Correlation analysis showed that adiponectin concentration was negatively correlated with mean blood pressure (P < 0.01). (3) Multivariate regression analysis revealed that mean blood pressure and HOMA-IR were independent predictors of serum adiponectin level.
Conclusions:
Mean blood pressure was the main determinant of serum adiponectin level and negatively correlated to serum adiponectin level.
Related Concept Videos
Blood Pressure
Blood Pressure
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the diastolic...
Factors affecting Blood pressure
Physiological Factors:
Measurement of Blood Pressure
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Pre-Procedural Guidelines for Assessing Blood Pressure