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Related Experiment Video

Updated: Jul 12, 2026

Interview: Glycolipid Antigen Presentation by CD1d and the Therapeutic Potential of NKT cell Activation

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Published on: December 31, 2007

Immune-mediated diseases: where do we stand?

Michael R Shurin¹, Yuri S Smolkin

¹Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA. shurinmr@upmc.edu

Advances in Experimental Medicine and Biology

|August 24, 2007

Summary

This summary is machine-generated.

Clinical immunology emerged from basic immunology, focusing on diagnosing and treating immune-mediated diseases. These conditions, including autoimmune and allergic diseases, pose significant global health and economic challenges.

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Area of Science:

Immunology
Clinical Immunology

Background:

The field of immunology has advanced significantly over the past 50-60 years.
This progress led to the establishment of clinical immunology as a distinct discipline in the 1970s.

Purpose of the Study:

To define clinical immunology as the application of basic immunology principles.
To highlight its role in diagnosing and treating immune-mediated diseases.

Main Methods:

N/A - This abstract describes the emergence and scope of a field, not a specific study's methods.

Main Results:

Immune-mediated diseases like autoimmune diseases, allergic diseases, and asthma are major global health concerns.
Autoimmune diseases affect 5-8% of the US population.
Asthma and allergic diseases are leading causes of chronic illness and disability in the US, particularly among children.

Conclusions:

Immune-mediated disorders cause profound personal suffering and significant economic burdens worldwide.
The impact of these diseases extends beyond statistics, affecting individuals, families, communities, and global economies.