Related Experiment Video
Updated: Jul 12, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
Sensory neural targets for the treatment of cough
Stuart B Mazzone1, Alice E McGovern
1Howard Florey Institute, University of Melbourne, Melbourne, Victoria, Australia. smazzone@florey.edu.au
Abstract:
1. Cough is a primary defensive reflex that protects the airways from potentially harmful stimuli. 2. During many respiratory diseases, the cough reflex threshold is lowered and coughing becomes excessive. 3. Currently available therapeutics are mostly ineffective at suppressing excessive coughing. 4. In the present review, we describe the sensory neural pathways involved in cough, how these pathways may become dysfunctional in airway disease and the most recent advances that have been made in identifying future targets for cough suppression.
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