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Epilepsy in children in Navarre, Spain: epileptic seizure types and epileptic syndromes
Teodoro Durá-Travé1, María Eugenia Yoldi-Petri, Fidel Gallinas-Victoriano
1Pediatric Neurology Unit, Virgen del Camino Hospital, Avenue Pio XII, 10-8oC, Pamplona, Spain. tduratra@cfnavarra.es
Insights
This study analyzed 365 children diagnosed with epilepsy, finding varied etiologies and seizure types. Pediatric epilepsy syndromes differ significantly across age groups, from West syndrome in infants to benign epilepsies in older children and adolescents.
Area of Science:
- Pediatric Neurology
- Epileptology
- Childhood Neurological Disorders
Background:
- Epilepsy is a common neurological disorder in children, characterized by recurrent seizures.
- Understanding the diverse etiologies and seizure types is crucial for effective management.
- Epidemiological data on pediatric epilepsy syndromes can inform clinical practice and research.
Purpose of the Study:
- To describe the epidemiological characteristics of childhood epilepsy.
- To analyze the distribution of epilepsy etiologies and seizure types in pediatric patients.
- To identify prevalent epilepsy syndromes across different age groups in childhood.
Main Methods:
- Retrospective data collection from 365 children diagnosed with epilepsy between 1 month and 15 years of age.
- Diagnosis of epilepsy based on International League Against Epilepsy criteria.
- Analysis of etiological categories (idiopathic, cryptogenic, symptomatic) and seizure types (focal, generalized).
Main Results:
- Idiopathic epilepsy was the most common etiology (45.5%), followed by cryptogenic (29.0%) and symptomatic (25.5%).
- Focal seizures (52.9%) were more prevalent than generalized epilepsy (43.5%).
- Prevalent syndromes varied by age: West syndrome in infants, cryptogenic focal epilepsies in early childhood and adolescence, and benign epilepsies/absences in school-aged children.
Conclusions:
- Childhood epilepsy presents with diverse etiologies and seizure patterns.
- Epilepsy syndrome prevalence significantly differs across developmental stages in children.
- These findings highlight the importance of age-specific approaches in diagnosing and managing pediatric epilepsy.
Abstract:
Data for children 1 month to 15 years of age at the time of diagnosis of epilepsy were recorded from the children's hospital "Virgen del Camino" in Pamplona (Spain) from January to December 2005. International League Against Epilepsy criteria were used for diagnoses. A total of 365 children were recruited into the study. Mean age at diagnosis was 5.97 years, and time of follow-up was 4.6 years. Etiology was idiopathic in 166 (45.5%), cryptogenic in 106 (29.0%), and symptomatic in 93 (25.5%). Focal seizures were seen in 52.9% of the patients, generalized epilepsy in 43.5%, and 3.6% were not determined. In infants, West syndrome (34.1%) and focal symptomatic seizures (24.4%) were the most prevalent syndromes. In early childhood, the main syndromes were cryptogenic focal epilepsies (17.7%) and Doose syndrome (12.8%). In school-aged children, benign epilepsies (27.3%) and absences (24.5%) were prevalent. In adolescents, cryptogenic focal epilepsies (26.6%) and benign epilepsies (23.4%).
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