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Updated: Jul 12, 2026

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

Published on: January 15, 2018

Functionalized gold nanoparticles for drug delivery.

Gang Han¹, Partha Ghosh, Vincent M Rotello

¹Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA.

Nanomedicine (London, England)

|August 25, 2007

Summary

Functionalized gold nanoparticles offer unique advantages for drug delivery. This review highlights recent advances in using these nanoparticles as carriers for therapeutic agents.

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Area of Science:

Nanotechnology
Materials Science
Pharmaceutical Sciences

Background:

Gold nanoparticles (AuNPs) possess unique physicochemical properties.
Their nanoscale dimensions and surface characteristics are advantageous for biological applications.

Purpose of the Study:

To review recent advancements in drug delivery systems utilizing functionalized gold nanoparticles.
To highlight the potential of AuNPs as carriers for therapeutic agents.

Main Methods:

Literature review of recent research on gold nanoparticle-based drug delivery.
Analysis of studies focusing on functionalization strategies and drug release mechanisms.

Main Results:

Functionalized gold nanoparticles demonstrate tunable surface properties.
Controllable drug release kinetics can be achieved with AuNP carriers.
AuNPs show promise for targeted and efficient therapeutic agent delivery.

Conclusions:

Functionalized gold nanoparticles are highly promising for advanced drug delivery applications.
Continued research in this field is expected to yield novel therapeutic strategies.