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Related Concept Videos

Production of Antibiotics01:27

Production of Antibiotics

Penicillin, one of the earliest and most widely used antibiotics, is produced industrially by the filamentous fungus Penicillium chrysogenum. Large stirred-tank bioreactors ranging from tens to hundreds of thousands of liters maintain tightly controlled temperature, pH, and dissolved oxygen conditions to support fungal metabolism and maximize antibiotic yield. Penicillin is a secondary metabolite, synthesized primarily during the stationary growth phase, which requires a carefully managed...
Antibiotic Selection00:57

Antibiotic Selection

Overview
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Products: Biologics, Biosimilars and Interchangeables01:28

Drug Products: Biologics, Biosimilars and Interchangeables

Biologics, derived from living sources such as humans, animals, or microorganisms, represent a significant category of pharmaceuticals. These complex molecules, developed through advanced biotechnological methods or purified from natural sources, include essential medical treatments like insulin and growth hormones. The complexity of biologics arises from their large molecular structures and the intricate processes required for their production, making them distinct from conventional...
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Inhibitors of Bacterial Protein Synthesis01:25

Inhibitors of Bacterial Protein Synthesis

Aminoglycosides constitute a highly potent class of bactericidal antibiotics that exert their antimicrobial effects by targeting the bacterial ribosome, specifically disrupting protein synthesis. These polycationic molecules consist of amino-modified sugars linked via glycosidic bonds to an aminocyclitol core such as 2-deoxystreptamine or streptamine. Their strong positive charges facilitate tight binding to the negatively charged phosphate backbone of ribosomal RNA (rRNA), primarily at the 16S...

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Related Experiment Video

Updated: Jul 12, 2026

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients

Published on: October 15, 2017

Zyvex Corporation.

Gareth A Hughes1, Meghana Honnatti

  • 1Zyvex Corporation, Richardson, TX 75081, USA. ghughes@zyvex.com

Nanomedicine (London, England)
|August 25, 2007
PubMed
Summary

Zyvex pioneers molecular nanotechnology, offering tools for precise manufacturing in biomaterials and microsystems. Their innovations aim to advance nanomedicine by enabling exploration and enhancement of biological nanosystems.

Area of Science:

  • Molecular nanotechnology
  • Biomedical engineering
  • Nanomedicine

Background:

  • Founded in 1997, Zyvex is a pioneering molecular nanotechnology company.
  • Nanotechnology is integral to biological systems, from cellular membranes to proteins.
  • Understanding and manipulating biological nanosystems is key to advancing nanomedicine.

Purpose of the Study:

  • To establish Zyvex as a leading supplier of tools and services for molecularly precise manufacturing.
  • To highlight the applications of Zyvex's nanotechnology in biomaterials, biomedical implants, and microsystems.
  • To underscore the necessity of nanotechnology tools for the advancement of nanomedicine.

Main Methods:

  • Development of adaptable, affordable, and molecularly precise manufacturing tools.

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Synthesis and Assay of Vibrio Quorum Sensing Inhibitors
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Synthesis and Assay of Vibrio Quorum Sensing Inhibitors

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Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients

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High Throughput, Real-time, Dual-readout Testing of Intracellular Antimicrobial Activity and Eukaryotic Cell Cytotoxicity

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Synthesis and Assay of Vibrio Quorum Sensing Inhibitors

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  • Application of nanotechnology in biomaterials and subcellular characterization.
  • Integration of nanomaterial composites for biomedical implants and 3D microsystems.

    • Main Results:

    • Zyvex technology is currently utilized in biomaterials, subcellular characterization, and nanomaterial composites for biomedical implants.
    • The company provides 3D microsystems for miniature instrumentation.
    • The company's vision is to be a global supplier enabling precise molecular manufacturing.

    Conclusions:

    • Nanotechnology tools are essential for exploring, characterizing, and enhancing biological nanosystems.
    • The potential of nanomedicine can be fully realized through advancements in molecular nanotechnology.
    • Zyvex is positioned to be a key player in the development and application of nanotechnology for medical and manufacturing purposes.