Related Experiment Video
Updated: Aug 6, 2026
13:19
Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 3, 2013
[Selection criteria for radical prostatectomy with reference to long-term results]
H Frohmüller1, M Wirth, A Manseck
1Urologische Klinik und Poliklinik, Universität Würzburg.
Der Urologe. Ausg. A
|November 1, 1991
Summary
Radical prostatectomy offers excellent long-term survival for prostate cancer patients, with rates comparable to the general population. Many patients, even with advanced disease, experience long-term tumor-free survival post-surgery.
Area of Science:
- Urology
- Oncology
- Surgical Oncology
Context:
- Radical prostatectomy is a primary treatment for prostate cancer.
- Long-term outcomes data are crucial for evaluating surgical efficacy.
- TNM classification (1979) was used for staging.
Purpose:
- To evaluate the long-term survival rates of patients undergoing radical prostatectomy for prostate cancer.
- To compare survival outcomes with the general male population.
Summary:
- A study of 410 prostate cancer patients treated with radical prostatectomy between 1969 and 1991 showed survival rates similar to the age-matched general population.
- 10-year survival rates for pT1pN0M0 and pT2pN0M0 tumors were 90.5% and 70%, respectively.
- For pT3pN0M0 tumors, the 10-year survival rate was 60%, with 40% tumor-free survivors, indicating potential cure.
Impact:
- Radical prostatectomy demonstrates favorable long-term oncological outcomes for localized prostate cancer.
- The procedure offers a chance for cure even in some cases with locally advanced disease.
- Findings support radical prostatectomy as an effective treatment option for selected prostate cancer patients.
