The effect of a slow flicker on the human photopic oscillatory potentials

Flicker-induced modifications of the human photopic oscillatory potentials (OPs) were investigated with the use of flash stimuli of 0.89 and 8.9 cd m-2 sec in strength. When the dimmest stimulus is used, increasing the rate of presentation from 0.5 to 20 Hz augments the amplitude and peak time of OP2. For a brighter stimulus, the 10 Hz flicker significantly reduces the amplitude of OP2 and OP3, increases the peak time of OP2 and reduces that of OP4. The 20 Hz flicker increases the peak time and reduces the amplitude of OP2 and completely abolishes OP3, while it has no significant impact on the amplitude and timing of OP4. The data presented support the claim that each OP making the photopic response represent independent electrophysiological entities.