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Updated: Jul 12, 2026

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
Published on: September 16, 2011
[Drug allergies and drug hypersensitivities]
1Unité d'exploration des allergies, maladies respiratoires - Inserm, hôpital Arnaud de Villeneuve, CHU de Montpellier, 34295 Montpellier Cedex 5. demoly@montp.inserm.fr
Abstract:
Drug hypersensitivities (also known as drug intolerances), including allergic reactions, are one of the side effects of drugs. If urticaria and maculopapular eruptions are the most frequent manifestations, then clinical forms are heterogeneous. The tools allowing a definite diagnosis include a thorough clinical history, standardised skin tests and drug provocation tests. Biological tests are being evaluated. When properly performed in specialised centres, a firm diagnosis is often possible and safe alternative medication can be proposed.
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