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Plasma histamine levels in laminitic horses and in horses treated with a corticosteroid
R Rautschka1, C Stanek, P F Knezevic
1Clinic of Orthopaedics in Ungulates, University of Veterinary Medicine, Vienna, Austria.
Zentralblatt Fur Veterinarmedizin. Reihe A
|November 1, 1991
Abstract:
In seven sound horses histamine plasma levels were evaluated by means of a radioenzymatic method using the enzyme histamine-N-methyltransferase (mean = 4.46 nmol/l, SD = 1.55 nmol/l). Histamine levels of laminitic horses were significantly higher (n = 11; mean = 12.46 nmol/l, SD = 3.24 nmol/l). In three sound horses plasma histamine levels were determined over a two week period following a double administration of 10 mg dexamethasone-21-isonicotinate/100 kg body weight. Histamine levels remained within the range of sound control horses.