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Annual report of the Australian Meningococcal Surveillance Programme, 2006

    Communicable Diseases Intelligence Quarterly Report
    |August 30, 2007
    PubMed

    Insights

    Invasive meningococcal disease cases decreased in 2006, primarily due to fewer serogroup B infections. Serogroup B remained dominant in young children and adolescents, while serogroup C affected young adults most.

    Area of Science:

    • Microbiology
    • Epidemiology
    • Public Health

    Background:

    • Invasive meningococcal disease (IMD) is a significant public health concern.
    • Neisseria meningitidis is the causative agent, with varying serogroups and phenotypes circulating globally.
    • Monitoring IMD epidemiology and antimicrobial resistance is crucial for effective control.

    Purpose of the Study:

    • To analyze the epidemiology and antimicrobial susceptibility of invasive meningococcal disease cases in Australia during 2006.
    • To identify dominant serogroups, phenotypes, and trends in IMD cases.
    • To assess antibiotic resistance patterns of Neisseria meningitidis isolates.

    Main Methods:

    • Laboratory confirmation of 271 invasive meningococcal disease cases.
    • Phenotypic characterization (serogroup, serotype, serosubtype) of 166 Neisseria meningitidis isolates.
    • Antibiotic susceptibility testing of isolates.

    Main Results:

    • A total of 271 confirmed cases were reported, a 21% decrease from 2005.
    • Serogroup B accounted for 80% of cases, followed by serogroup C (9.6%).
    • Decreased susceptibility to penicillin was observed in two-thirds of isolates, but all remained susceptible to rifampicin and ciprofloxacin.

    Conclusions:

    • Invasive meningococcal disease incidence declined in Australia in 2006, with serogroup B remaining the most prevalent.
    • Distinct age-related patterns were observed for serogroups B and C.
    • Monitoring antimicrobial susceptibility is essential for guiding treatment strategies.

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