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[Update in drug therapy in neuropediatry]
P Leroy1, J M Dubru, J P Misson
1Service de Neuropédiatrie, CHR Citadelle, CHU Sart-Tilman, Liège, Belgique.
Insights
Newer antiepileptic drugs like lamotrigine and levetiracetam are effective for childhood seizures but have restricted reimbursement in Belgium. Atomoxetine offers a new treatment option for attention deficit hyperactivity disorder (ADHD) beyond methylphenidate.
Area of Science:
- Pediatric Neurology
- Pharmacology
Context:
- Recent advancements in pediatric pharmacotherapy.
- Limited access to antiepileptic drugs (AEDs) in Belgium.
- Evolving treatment landscape for attention deficit hyperactivity disorder (ADHD).
Purpose:
- To review the efficacy and accessibility of recent AEDs in children.
- To introduce atomoxetine as an alternative ADHD treatment.
- To highlight Belgian reimbursement policies for pediatric medications.
Summary:
- Lamotrigine, topiramate, oxcarbazepine, and levetiracetam are recent AEDs with proven efficacy for various seizure types in children.
- Reimbursement for these AEDs in Belgium is conditional, impacting treatment accessibility.
- Atomoxetine presents a novel therapeutic option for pediatric ADHD, distinct from traditional methylphenidate treatment.
Impact:
- Informs clinical practice regarding AED selection and access in Belgium.
- Expands treatment options for children with ADHD.
- Highlights the importance of medication accessibility and reimbursement policies in pediatric care.
Abstract:
The most recent antiepileptic drugs used in children are lamotrigine, topiramate, oxcarbamaz6pine and levetiracetam. Their efficacy is proven, depending on the type of crisis, but in Belgium they are reimbursed only in certain conditions. The treatment of children with attention deficit hyperactivity disorder (ADHD), which was only constituted of methylphenidate, can now benefit from atomoxetine whose mechanism of action is different.
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