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Updated: Jul 12, 2026
Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
[Retinal capillary blood flow in exudative age-related macular degeneration]
Izabela Nowak1, Magdalena Pilas-Pomykalska, Janusz Czajkowski
1Kliniki Chorób Oczu Katedry Chorób Oczu Uniwersytetu Medycznego w Łodzi.
Purpose:
The purpose of this study was to evaluate retinal capillary blood flow in patients with exudative AMD.
Material And Methods:
Twenty patients with exudative AMD and twenty four patients age-matched control subjects, were included into the study. Retinal capillary blood flow was evaluated with Heidelberg Retinal Flowmeter (HRF), measurements were taken in two macular regions. The total mean flow and mean velocity were calculated usingthe technique of automatic full field perfusion image analysis (AFFPIA). The U Mann-Whitney test was used for statistical analysis.
Results:
Patients with exudative AMD revealed slightly lower retinal blood flow than control subjects in area I and in area II. In the AMD group total mean flow values were: 295.75 AU/ 303.85 AU, while in the control group were: 302.37 AU/ 304.42 AU. The mean velocity values were: 1.48 AU/ 1.42 AU in AMD patients and: 1.49 AU/ 1.52 AU in control group. The differences did not reach the statistical significance.
Conclusions:
The study results showed no changes in retinal capillary blood flow in patients with exudative AMD comparing to normal subjects.
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